Building the evidence for the use of bacteriophage therapy

Overview
Bacteriophages (phages) are a promising tool for addressing antimicrobial resistance, targeting harmful bacteria without disrupting beneficial microbiota. Safe for humans, they can enhance antibiotic treatments, particularly against resistant bacteria. The WHO Regional Office for Europe and the Global Antimicrobial Resistance Research and Development Hub are advancing evidence for phage applications through the “Vintage Innovation” initiative, adopting a One Health approach across human, animal and environmental sectors. This report summarizes outcomes from a number of activities, including webinars, expert consultations and a dedicated workshop that took place in Tbilisi, Georgia, on advancing the evidence for bacteriophages use.