WHO working group on late-stage development for malaria vaccines to reduce disease burden

Overview

On 12 and 19 April 2021, a WHO working group on late-stage development of malaria vaccines to reduce disease burden was convened by the WHO Department of Immunization, Vaccines and Biologicals (IVB) and the Global Malaria Programme (GMP). The goal of the working group was to review priority phase 3 research and development considerations for the path to licensure and wide-scale implementation of vaccines. Experts reviewed key issues related to preclinical and phase 1 and 2 studies, phase 3 trial design, and manufacturing and production for wide-scale implementation.