Guidelines for the prevention, diagnosis, care and treatment for people with chronic hepatitis B infection

Overview
Hepatitis B (HBV) infection is a major public health problem and cause of chronic liver disease.
The 2024 HBV guidelines provide updated evidence-informed recommendations on key priority topics. These include expanded and simplified treatment criteria for adults but now also for adolescents; expanded eligibility for antiviral prophylaxis for pregnant women to prevent mother-to-child transmission of HBV; improving HBV diagnostics through use of point-of-care HBV DNA viral load and reflex approaches to HBV DNA testing; who to test and how to test for HDV infection; and approaches to promote delivery of high-quality HBV services, including strategies to promote adherence to long-term antiviral therapy and retention in care.
The 2024 guidelines include 11 updated chapters with new recommendations and also update existing chapters without new recommendations, such as those on treatment monitoring and surveillance for liver cancer.
Policy brief
Web annexes
Web annex B: evidence-to-decision making tables and GRADE tables (PDF, 1.2 MB)
Web annex C: systematic reviews, modelling, and landscape reports (PDF, 4.5 MB)
Web annex D: values and preferences survey reports (PDF, 830 KB)
Webinar
Recording: Hepatitis B – WHO's webinar on its 2024 guidelines
Slides: technical briefing presentations (PDF, 7.5 MB)
Related
WHO publishes new guidelines on hepatitis B – Departmental news, 29 March 2024
WHO 2024 hepatitis B guidelines: an opportunity to transform care – The Lancet Gastroenterology & Hepatology, 10 April 2024