Generic protocol: a prospective cohort study investigating maternal, pregnancy and neonatal outcomes for women and neonates infected with SARS-CoV-2

Overview

This document has been superseded by a newer version (version 3.1) dated 1 November 2022. Access the new version here.

The purpose of this study is to determine if SARS-CoV-2 infection during pregnancy increases the risk of adverse pregnancy, post-partum or neonatal outcomes. Additionally, the study will characterize the clinical spectrum of COVID-19 in pregnant women, quantify (if any) the rate of in utero/intra-partum/postnatal transmission, determine the incidence of detectable SARS-CoV-2 RNA in pregnancy-related fluids (i.e. amniotic fluid), breast milk and tissues, and follow clinical outcomes of women and their newborns up to 6 weeks after childbirth.