Point-of-care CD4 tests to support the identification of individuals with advanced HIV disease

Overview

Despite increases in access to antiretroviral therapy (ART), declines in AIDS-related deaths have plateaued in recent years. Even after starting ART, patients with severe immunosuppression have a high risk of death. Implementing a package of care for patients with advanced HIV disease is critical; however, identifying those in need has remained a challenge.

This target product profile describes the optimal and minimal product characteristics of an ideally device-free point- of-care test that enables health- care providers caring for people living with HIV older than five years to screen for advanced HIV disease by determining CD4 count.

Related links

• Guidelines for managing advanced HIV disease and rapid initiation of antiretroviral therapy
• Prequalification of in vitro diagnostics
• HIV treatment and care