Global Antimicrobial Resistance Surveillance System (GLASS). Molecular methods for antimicrobial resistance (AMR) diagnostics to enhance the Global Antimicrobial Resistance Surveillance System
Overview
Antimicrobial resistance (AMR) is a serious threat to global public
health. In 2015, WHO launched the Global Antimicrobial Resistance
Surveillance System (GLASS) in order to standardize the collection of
data on AMR for planning, prevention and intervention programmes.
Reports to GLASS currently rely on detection of phenotypic resistance,
however in the future, GLASS may incorporate the results of molecular
testing for AMR detection by appropriate methods. Molecular diagnostic
methods can be used with phenotypic testing to yield additional
information.
This technical note provides information to those involved
at various levels of AMR surveillance in choosing the most appropriate
molecular AMR test for their setting, including clinical and reference
laboratories. The document also provides a review of available methods
and how they could be used in national surveillance.
