CESTA: Cervical cancer screening and treatment algorithms study using HPV testing in Africa

Overview

WHO updated the cervical cancer screening and treatment guidelines in 2014 and included primary screening options with VIA and HPV testing. Although the guidelines were evidence-based, the available data that was used to derive the recommendations was scanty, principally in low resource settings. They identified a research gap for clinically relevant studies for the screening algorithms of interest.

Objective: to compare the performance of cervical cancer screening and treatment algorithms using primary HPV testing included in the WHO guidelines, but also including novel ways of screening and treatment of precancerous lesions.