Efficacy trials of ZIKV Vaccines: endpoints, trial design, site selection

On June 1-2, 2017, the WHO convened a group of about 30 experts in epidemiology, regulatory, preclinical and clinical vaccine trials, and mathematical modelling, in a workshop on planning for Zika vaccine efficacy trials.

The workshop aimed to define generic principles on how to best design, conduct and analyze vaccine trials against ZIKV, based on the available scientific evidence as well as on lessons learned from evaluating other flavivirus vaccines.