WHO R&D Blueprint – Ad-hoc Expert Consultation on clinical trials for Ebola Therapeutics

Overview

This expert consultation is convening representatives from EVD-at risk countries, international partner organizations supporting affected countries in establishing Ebola treatment centers (ETCs) and providing clinical care, partners and experts in the field of randomized controlled trials (RCTs) for evaluating investigational therapeutics (in particular clinical experts, trialists, and statisticians).

The objectives of this consultation were:

1. To discuss and outline potential criteria that could inform the evidence-based selection of therapeutic agents for clinical trials.

2. To review and critically appraise the existing evidence regarding different investigational therapeutics agents.

3. To discuss trial design options and reach consensus on the various options towards a robust study design.

4. To jointly outline a framework for an efficient collaborative approach across countries and outbreaks.