External Publications

The global landscape of country-level health technology assessment processes: A survey among 104 countries
To assess the practice of HTA in countries, WHO conducted a global survey that explores the status of HTA. The survey is the largest source of information...

The potential impact of novel tuberculosis vaccine introduction on economic growth in low- and middle-income...
Most individuals developing tuberculosis (TB) are working age adults living in low- and middle-income countries (LMICs). The resulting disability and death...

The Macroeconomic Impact of Increasing Investments in Malaria Control in 26 High Malaria Burden Countries:...
Malaria remains a major public health problem. While globally malaria mortality affects predominantly young children, clinical malaria affects all age...

Projected health-care resource needs for an effective response to COVID-19 in 73 low-income and middle-income...

Guide posts for investment in primary health care and projected resource needs in 67 low-income and middle-income...

Generalised cost-effectiveness analysis of 159 health interventions for the Ethiopian essential health...

Is Universal Health Coverage Affordable? Estimated Costs and Fiscal Space Analysis for the Ethiopian...

Revision of the Ethiopian Essential Health Service Package: An Explication of the Process and Methods...

The cost-effectiveness of banning highly hazardous pesticides to prevent suicides due to pesticide self-ingestion...

Are the “Best Buys” for Alcohol Control Still Valid? An Update on the Comparative Cost-Effectiveness...

The Economic Burden of Malaria: Revisiting the Evidence

Cost-effectiveness of clinical interventions for reducing the global burden of bipolar disorder
In this second article of the neonatal survival series, we identify 16 interventions with proven efficacy (implementation under ideal conditions) for neonatal...

Choosing cost-effective interventions in psychiatry: results from the CHOICE programme of the World Health...
This research report provides an overview of the mental health component of the World Health Organization's CHOICE project, the aim of which is to generate...

Uncertainty in cost-effectiveness analysis. Probabilistic uncertainty analysis and stochastic league...
Interest is growing in the application of standard statistical inferential techniques to the calculation of cost-effectiveness ratios (CER), but individual...

Cost-effectiveness analysis of cataract surgery: a global and regional analysis
To estimate the population health effects, costs and cost effectiveness of selected cataract surgery interventions in areas of the world with different...

Reducing the global burden of depression: Population-level analysis of intervention cost-effectiveness...

Distribution of road traffic deaths by road user group: a global comparison
To outline systematically the global distribution of road traffic deaths by road user groups (pedestrians, bicyclists, motorcyclists, motorised four-wheeler...

Chronic diseases and injuries in India
Chronic diseases (eg, cardiovascular diseases, mental health disorders, diabetes, and cancer) and injuries are the leading causes of death and disability...

Cost Effectiveness and Resource Allocation 2003
Estimating the costs of health interventions is important to policy-makers for a number of reasons including the fact that the results can be used as a...

Cost Effectiveness and Resource Allocation: Econometric estimation of country-specific hospital costs
Information on the unit cost of inpatient and outpatient care is an essential element for costing, budgeting and economic-evaluation exercises.

Achieving the WHO/UNAIDS antiretroviral treatment 3 by 5 goal: what will it cost?
The "3 by 5" goal to have 3 million people in low and middle income countries on antiretroviral therapy (ART) by the end of 2005 is ambitious.

Cost effectiveness analysis of strategies to combat HIV/AIDS in developing countries
To assess the costs and health effects of a range of interventions for preventing the spread of HIV and for treating people with HIV/AIDS in the context...

Cost effectiveness analysis of strategies for tuberculosis control in developing countries
To assess the costs and health effects of tuberculosis control interventions in Africa and South East Asia in the context of the millennium development...

Cost effectiveness analysis of strategies to combat malaria in developing countries
To determine the cost effectiveness of selected malaria control interventions in the context of reaching the millennium development goals for malaria.

Methods to assess the costs and health effects of interventions for improving health in developing countries
Assessment of the cost effectiveness of interventions designed to achieve the millennium development goals for health is complex. The methods must be capable...

Cost effectiveness analysis of strategies for child health in developing countries
To determine the costs and effectiveness of selected child health interventions—namely, case management of pneumonia, oral rehydration therapy, supplementation...

Evidence-based, cost-effective interventions: how many newborn babies can we save?
In this second article of the neonatal survival series, we identify 16 interventions with proven efficacy (implementation under ideal conditions) for neonatal...

Cost-effectiveness of an essential mental health intervention package in Nigeria
The study aimed to describe the cost-effectiveness of a selected list of interventions for common neuropsychiatric disorders in a developing country. Using...

Iron Fortification and Iron Supplementation are Cost-Effective Interventions to Reduce Iron Deficiency...
Iron deficiency is the most common and widespread nutritional disorder in the world, affecting millions of people in both nonindustrialized and industrialized...

Effectiveness and costs of interventions to lower systolic blood pressure and cholesterol: a global and...
Cardiovascular disease accounts for much morbidity and mortality in developed countries and is becoming increasingly important in less developed regions....

Economic evaluation in health: saving money or improving care?
Economic evaluation, most commonly in the form of cost-effectiveness analysis, has now become an established tool of overall health financing policy. However,...

Critical issues in the economic evaluation of interventions against communicable diseases
Economic appraisal seeks to provide policy-makers with guidance about how scarce resources can be used to derive the greatest possible social benefit.

Global health worker salary estimates: an econometric analysis of global earnings data
Human resources are consistently cited as a leading contributor to health care costs; however the availability of internationally comparable data on health...

Resource Needs for Addressing Noncommunicable Disease in Low- and Middle-Income Countries: Current and...
Low and middle income countries are faced with a range of challenges related to providing efficient and affordable health care. With non-communicable diseases...

Accounting for the cost of scaling‐up health interventions
Recent studies such as the Commission on Macroeconomics and Health have highlighted the need for expanding the coverage of services for HIV/AIDS, malaria,...

PopMod: a longitudinal population model with two interacting disease states
This article provides a description of the population model PopMod, which is designed to simulate the health and mortality experience of an arbitrary population...

Financing transformative health systems towards achievement of the health Sustainable Development Goals:...
he ambitious development agenda of the Sustainable Development Goals (SDGs) requires substantial investments across several sectors, including for SDG...

Cost-effectiveness of screening and correcting refractive errors in school children in Africa, Asia,...
To estimate the costs and effects of alternative strategies for annual screening of school children for refractive errors, and the provision of spectacles,...

Advancing social and economic development by investing in women's and children's health: a new Global...

Capacity utilization and the cost of primary care visits: Implications for the costs of scaling up health...
The main objective of this paper is to measure the impact of patient load on the cost per visit at primary health care facilities and the extent to which...

Scale up services for mental disorders: a call for action
We call for the global health community, governments, donors, multilateral agencies, and other mental health stakeholders, such as professional bodies...

Time to reassess strategies for improving health in developing countries
Improving health received considerable prominence in the millennium development goals. Three of the eight goals focused on reducing key causes of mortality...

Cost effectiveness analysis of strategies for maternal and neonatal health in developing countries
To determine the costs and benefits of interventions for maternal and newborn health to assess the appropriateness of current strategies and guide future...

Grading quality of evidence and strength of recommendations
Clinical guidelines are only as good as the evidence and judgments they are based on. The GRADE approach aims to make it easier for users to assess the...

Effectiveness and cost of facility-based Integrated Management of Childhood Illness (IMCI) in Tanzania
The Integrated Management of Childhood Illness (IMCI) strategy is designed to address major causes of child mortality at the levels of community, health...

World health system performance revisited: the impact of varying the relative importance of health system...
In 2002, the World Health Organization published a health system performance ranking for 191 member countries. The ranking was based on five indicators,...

Methods to assess the costs and health effects of interventions for improving health in developing countries:...
Assessment of the cost effectiveness of interventions designed to achieve the millennium development goals for health is complex.

Breastfeeding patterns and exposure to suboptimal breastfeeding among children in developing countries:...
Suboptimal breastfeeding is associated with higher mortality among infants and young children in the developing world.

Effectiveness and cost-effectiveness of policies and programmes to reduce the harm caused by alcohol
This paper reviews the evidence for the effectiveness and cost-effectiveness of policies and programmes to reduce the harm caused by alcohol, in the areas...

Costs and health effects of breast cancer interventions in epidemiologically different regions of Africa,...
We estimated the costs and health effects of treating stage I, II, III, and IV breast cancer individually, of treating all stages, and of introducing an...

Determinants of variation in the cost of inpatient stays versus outpatient visits in hospitals: a multi-country...
Information on hospital costs is key to many types of economic and financial analyses, yet many countries lack reliable estimates due partly to the time...

WHO Framework Convention on Tobacco Control:development of an evidence based global public health treaty
Many health problems require international action, but getting governments to agree on strategies for prevention or treatment is difficult. By making use...

Tackling of unhealthy diets, physical inactivity, and obesity: health effects and cost-effectiveness

Enhancing the comparability of costing methods: cross-country variability in the prices of non-traded...
National and international policy makers have been increasing their focus on developing strategies to enable poor countries achieve the millennium development...

A financial road map to scaling up essential child health interventions in 75 countries
To estimate the additional resources required to scale up interventions to reduce child mortality and morbidity within the context of the fourth Millennium...

Estimated global resources needed to attain universal coverage of maternal and newborn health services
To estimate the amount of additional resources needed to scale up maternal and newborn health services within the context of the Millennium Development...

Cost of scaling up mental healthcare in low- and middle-income countries
To estimate the expenditures needed to scale up the delivery of an essential mental healthcare package over a 10-year period (2006-2015).

Prevention of cardiovascular disease in high-risk individuals in low-income and middle-income countries:...
Scaling up coverage of evidence-based interventions to prevent cardiovascular disease in high-risk individuals in low-income and middle-income countries...

Chronic disease prevention: health effects and financial costs of strategies to reduce salt intake and...
In 2005, WHO set a global goal to reduce rates of death from chronic (non-communicable) disease by an additional 2% every year. To this end, we investigated...

The burden and costs of chronic diseases in low-income and middle-income countries
This paper estimates the disease burden and loss of economic output associated with chronic diseases—mainly cardiovascular diseases, cancer, chronic respiratory...

Generalized cost-effectiveness analysis for national-level priority-setting in the health sector
Cost-effectiveness analysis (CEA) is potentially an important aid to public health decision-making but, with some notable exceptions, its use and impact...

Cost-Effectiveness of Interventions to Improve Maternal, Newborn and Child Health Outcomes: A WHO-CHOICE...

Progressive Realisation of Universal Health Coverage in Low- and Middle-Income Countries: Beyond the...
World Health Organization Choosing Interventions that are Cost-Effective (WHO CHOICE) has been a programme of the WHO for 20 years. In this latest update,...

Methods for the Economic Evaluation of Health Care Interventions for Priority Setting in the Health System:...
This paper provides an overview of the methodological approach, updates to analytic framework over the past 10 years, and the added value of the WHO-CHOICE...

Priority Setting in HIV, Tuberculosis, and Malaria – New Cost-Effectiveness Results From WHO-CHOICE
This paper forms part of an update of the World Health Organization Choosing Interventions that are Cost-Effective (WHO-CHOICE) programmes. It provides...

Screening, prevention and treatment of cervical cancer -- a global and regional generalized cost-effectiveness...
The paper calculates regional generalized cost-effectiveness estimates of screening, prevention, treatment and combined interventions for cervical cancer.

Education and debate
Achieving the millennium development goals for health. Evaluation of current strategies and future priorities for improving health in developing...

Comparative cost-effectiveness of policy instruments for reducing the global burden of alcohol, tobacco...

Costs, health effects and cost-effectiveness of alcohol and tobacco control strategies in Estonia

Generalized cost-effectiveness analysis for national-level priority-setting in the health sector

Programme costs in the economic evaluation of health interventions
Estimating the costs of health interventions is important to policy-makers for a number of reasonsincluding the fact that the results can be used as a...

Economic impact of disease and injury: counting what matters

Prevention, screening and treatment of colorectal cancer: a global and regional generalized cost effectiveness...

Cost-effectiveness analysis of interventions to prevent cardiovascular disease in Vietnam

Intervention strategies to reduce the burden of non-communicable diseases in Mexico: cost effectiveness...

Cost effectiveness of strategies to combat road traffic injuries in sub-Saharan Africa and South East...

Cost effectiveness of strategies to combat neuropsychiatric conditions in sub-Saharan Africa and South...

Cost effectiveness of strategies to combat vision and hearing loss in sub-Saharan Africa and South East...

Cost effectiveness of strategies to combat chronic obstructive pulmonary disease and asthma in sub-Saharan...

Cost effectiveness of strategies to combat cardiovascular disease, diabetes, and tobacco use in sub-Saharan...

Cost effectiveness of strategies to combat breast, cervical, and colorectal cancer in sub-Saharan Africa...

Econometric estimation of WHO-CHOICE country-specific costs for inpatient and outpatient health service...


