Mental Health, Brain Health and Substance Use
Our work involves mental health promotion and the prevention of mental, neurological and substance use disorders. We support the expansion of access to affordable, quality care for everyone who needs it.
Pharmacological interventions (antidepressants) for people with dementia who have associated depression
[2015]
Recommendation(s)
In people with dementia and severe depression, or when psychosocial interventions prove ineffective, the use of selective serotonin reuptake inhibitors (SSRIs) (but not tricyclic antidepressants [TCAs]) may be considered.
In people with dementia and mild to moderate depression, antidepressants should not be offered as a first-line treatment.
Strength of recommendation: CONDITIONAL
Quality of evidence: LOW