WHO Human Health Risk Assessment Toolkit: Chemical Hazards
IPCS harmonization project document no. 8

Overview
The purpose of the WHO Human Health Risk Assessment Toolkit: Chemical Hazards is to
provide its users with guidance to identify, acquire and use the information needed to assess
chemical hazards, exposures and the corresponding health risks in their given health risk
assessment contexts at local and/or national levels.
The Toolkit provides road maps for
conducting a human health risk assessment, identifies information that must be gathered to
complete an assessment and provides electronic links to international resources from which
the user can obtain information and methods essential for conducting the human health risk
assessment.
By doing so, the Toolkit also aims at raising awareness and promoting the use of globally
accepted risk assessment information that has been developed by international organizations
such as WHO, the Food and Agriculture Organization of the United Nations, the United
Nations Environment Programme, the Codex Alimentarius Commission and OECD for use in
countries.
The Toolkit has been developed for public health and environmental professionals,
regulators, industrial managers and other decision-makers with at least some training in the
principles of risk assessment who are responsible for conducting human health risk
assessments and making decisions on whether to take action to manage human health risks
associated with exposure to chemicals.
WHO and all those involved in the development of the publication hope that the Toolkit will
have wide application, especially in developing countries and countries with economies in
transition.
In the future, it is hoped that, in these countries, the identification of human health
risks related to chemicals as well as related management decisions and mitigation measures,
including those related to international agreements, are based on best evidence through the
application of best risk assessment methodology and use of available authoritative risk
assessment information developed by international organizations in combination with locally
relevant information.
Link to the second edition (2021)