Preparing and preventing epidemics and pandemics

The number of high-threat infectious hazards continues to rise; some of these are re-emerging and others are new. While outbreaks of vaccine-preventable infectious diseases, such as meningococcal disease, yellow fever and cholera, can have disastrous effects in areas with limited health infrastructure and resources, and where timely detection and response is difficult.

WHO develops global strategies for the prevention and control of epidemic-prone diseases, such as yellow fever, cholera and influenza. With partners from a wide range of technical, scientific and social fields, WHO brings together all globally available resources to counter these high-threat infectious hazards and scale these strategies to regional and country levels. 

Flagship global strategies include: 

  • the Eliminate Yellow Fever Epidemics strategy 2017-2026;
  • Ending Cholera: a Global Roadmap to 2030;
  • the Pandemic Influenza Preparedness (PIP) Framework; and 
  • the Global Strategy for Influenza 2018-2030.

WHO is also the secretariat for the governance of global emergency stockpiles, including the International Coordinating Group on Vaccine Provision, which manages and coordinates the provision of emergency vaccine supplies and antibiotics to countries during major outbreaks.

Publications

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Considerations for use of avian influenza A(‎H5)‎ vaccines during the interpandemic and emergence periods: report of a WHO virtual scientific consultation, September 2024

WHO conducted a virtual scientific expert consultation on A(H5) vaccines and vaccination. This report provides an overview of the landscape of A(H5) vaccines...

Respiratory syncytial virus sequencing considerations for an expanded Global Influenza Surveillance and Response System

In recent years, rapid progress has been made in the development of new pharmaceutical interventions against respiratory syncytial virus (RSV), including...

Meeting of the Strategic Advisory Group of Experts on Immunization, March 2025: Conclusions and recommendations

The Strategic Advisory Group of Experts on Immunization (SAGE) met on 10–13  March 2025. This report summarizes their discussions, conclusions,...

Strategic actions for infection prevention and control and water, sanitation and hygiene during mpox outbreak response

The mpox IPC and WASH strategy focuses on strengthening two major components of the response: 1) safe and scalable care within health-care facilities and...