Patrick Robert
Logo of the Central Trypanosomatosis Bureau in Kinshasa.
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Supporting endemic countries to eliminate human African trypanosomiasis

Control of human African trypanosomiasis (HAT) requires case detection followed by curative treatment to break the cycle of transmission by depleting the human reservoir (in the gambiense form), completed, if possible, by targeted vector control. National HAT control programmes are in the front-line of control and surveillance activities. WHO and other stakeholders, including bilateral cooperation agencies and nongovernmental and philanthropic organizations, support these efforts. The public–private partnership between WHO and the pharmaceutical companies Sanofi and Bayer has been reinforcing this support since 2001. 

We have seen how upholding this support over time can dramatically decrease the global incidence of HAT and possibly eliminate the disease. The support focuses on:

Case detection: screening exposed populations using serological tests, passively in health facilities and actively by mobile units; confirmatory diagnosis with microscopy. 

Case management: disease staging to determine the correct treatment; ensuring access to the best treatment available for all cases.

Surveillance: documenting all cases in place and time ( HAT Atlas), and tracking the situation at all levels to appropriately target field operations; maintaining sentinel sites in key health facilities.

Technical support and capacity‐building: assessing the local situation, selecting adapted techniques and strategies, and developing guidelines and support material for training and supervision.

 

57 million

People at risk in 36 countries

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977

cases in 2018

A record low

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95%

Percentage of case reduction since 2000

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Relevant publications

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Guidelines for the treatment of human African trypanosomiasis
These guidelines are providing updated evidence-based recommendations on therapeutic choices to ensure the best possible treatment for individuals infected...
Human African trypanosomiasis eliminated as a public health problem in Chad

Chad was validated for the elimination of gambiense  HAT as a public health problem in April 2024, and the work continues towards interrupting transmission...

Report of the fifth WHO stakeholders meeting on gambiense and rhodesiense human African trypanosomiasis elimination, Geneva, Switzerland, 7–9 June 2023

Concerted efforts by national programmes, supported by public–private partnerships, nongovernmental organizations, donors and academia under...