Global genomic surveillance strategy for pathogens with pandemic and epidemic potential 2022–2032
Genomic surveillance
Many people are familiar with the field of genomics as a tool for ancestry mapping to trace relatives or to identify genetic risk factors for diseases. However, genomics has also been widely applied to tracking infectious diseases by sequencing the genomes of bacteria, parasites and viruses. Genomic surveillance is the process of constantly monitoring pathogens and analyzing their genetic similarities and differences. Recognizing the need for global collaboration in strengthening genomic surveillance, WHO has coordinated the development of the 10-year Global genomic surveillance strategy for pathogens with pandemic and epidemic potential 2022 - 2032. The initiative is powered by a vision to unite, inform and strengthen genomic surveillance efforts at country, regional and global levels.
The Strategy
Strategy document
Global genomic surveillance strategy for pathogens with pandemic and epidemic potential, 2022–2032
The Strategy provides a high-level unifying framework to leverage existing capacities, address barriers and strengthen the use of genomic surveillance in the detection, monitoring and response to public health threats. Genomic surveillance is part of the broader surveillance and laboratory system, and its implementation should reinforce end-to-end capacities including sample collection, diagnostics, data sharing and analysis. The strategy aims to facilitate the connectivity between different disease control programs and surveillance networks. This interoperability will strengthen the cross-cutting essential public health laboratory functions underpinning genomics holistically. The strategy articulates the overarching goal, objectives and strategic actions needed. These are dependent on commitments from countries, partners and WHO for their implementation.
Progress report

Global genomic surveillance strategy for pathogens with pandemic and epidemic potential...
National strategy development: step by step guide

Considerations for developing a national genomic surveillance strategy or action plan for pathogens with pandemic and epidemic potential
This step by step guide outlines key considerations and a proposed approach for countries to develop a national genomic surveillance strategy or action plan for pathogens with pandemic and epidemic potential. This technical document is intended for use by all stakeholders at the national and subnational levels relevant to the development and implementation of the strategy, including health authorities, One Health partners, donors, public health officers, academia, the private sector and laboratory specialists.Monitoring strategy implementation
The key measure of the Strategy’s success is that, by 2032, all 194 Member States have timely access to genomic sequencing for pathogens with pandemic and epidemic potential. Member States are also encouraged to share SARS-CoV-2 genetic sequence data to a publicly accessible database to facilitate country, regional and global risk assessment. WHO is monitoring two indicators to track this progress, in line with the Strategy objectives.
Learn more about the WHO regional initiatives for strengthening genomic surveillance here.
Publications

WHO guiding principles for pathogen genome data sharing
WHO encourages the sharing of pathogen genome data to protect global public health. Sharing of pathogen genome data is critical for preventing, detecting,...

End-to-end integration of SARS-CoV-2 and influenza sentinel surveillance: revised interim guidance
This guidance provides interim guidance for the integration of SARS-CoV-2 and influenza virologic and genomic surveillance, from sentinel site case enrolment...
Stories from the field
Meetings
Global meeting on sustaining gains in genomics for managing pandemic and epidemic threats: Istanbul, Türkiye, 14–15 December 2023: report Global meeting on sustaining gains in genomics for managing pandemic and epidemic threats: Istanbul, Türkiye, 14–15 December 2023: report
Global workshop on enhancing sequencing to monitor SARS-CoV-2 evolution: report of a virtual meeting, 19 March 2021 Global workshop on enhancing sequencing to monitor SARS-CoV-2 evolution: report of a virtual meeting, 19 March 2021
WHO Consultation on the Global Genomic Surveillance Strategy for Pathogens with Pandemic and Epidemic Potential, 8 December 2021 WHO Consultation on the Global Genomic Surveillance Strategy for Pathogens with Pandemic and Epidemic Potential, 8 December 2021
Contact
Genomic surveillance strategy team
World Health Organization
20 Avenue Appia
1211 Geneva
Switzerland
Email: pathogengenomics@who.int