Global HIV, Hepatitis and STIs Programmes
The Department of Global HIV, Hepatitis and Sexually Transmitted Infections Programmes leads the development and implementation of the global health sector strategy on the elimination of the diseases as public health threats.

Trans and gender diverse people

Transgender people are around 13 times more likely to be HIV-positive than other adults of reproductive age. In some regions, transgender women account for disproportionally large shares of new infections, including Asia and the Pacific (7%), Latin America (6%) and the Caribbean (5%). HIV prevalence among transgender women is estimated to be 28.4% in Eastern and Southern Africa; 13.5% in Western and Central Africa; 22.2% in Latin America; and 23.7% in the Caribbean (UNAIDS, 2020). Little data is available for transgender men and other transgender populations regarding HIV epidemiology. Even less data is available regarding prevalence and incidence rates of viral hepatitis and other sexually transmitted infections (STIs) in transgender people.

Overall, transgender people have low rates of access to health services due to a range of issues including violence, legal barriers, stigma and discrimination.

Violence against transgender people is common. Furthermore, transgender people may experience family rejection and violation of their rights to education, employment and social protections. As such, they may experience higher rates of unemployment, poverty, housing insecurity and marginalization.

In most countries, a lack of legal recognition of transgender people contributes to their exclusion and marginalization. While a few countries now recognize a “third gender”, in many settings transgender people are required to undergo genital surgery to gain legal recognition of their gender. Other countries will never recognize a change to the gender assigned at birth.

WHO works with international and country partners to address the varied health needs of transgender people, including HIV, viral hepatitis and STI prevention, diagnosis and treatment. WHO also supports partners to address structural barriers that affect transgender people’s ability to access services.

A comprehensive package of services is recommended to address these infectious diseases in transgender people.

Essential for impact: enabling interventions

Essential for impact: health interventions

Essential for broader health: health interventions

 

  • Removing punitive laws, policies and practices
  • Reducing stigma and discrimination
  • Community empowerment
  • Addressing violence

Prevention of HIV, viral hepatitis and STIs

  • Condoms and lubricant
  • PrEP for HIV
  • PEP for HIV and STIs
  • Prevention of vertical transmission of HIV, syphilis and HBV
  • HBV vaccination
  • Addressing chemsex

Diagnosis

  • HIV testing services
  • STI testing
  • HBV and hepatitis C (HCV) testing 

Treatment

  • HIV treatment
  • Screening, diagnosis, treatment and prevention of HIV-associated tuberculosis (TB)
  • STI treatment 
  • HBV and HCV treatment

 

  • Anal health
  • Conception and pregnancy care
  • Contraception
  • Gender-affirming care
  • Mental health 
  • Prevention, assessment and treatment of cervical cancer
  • Safe abortion
  • Screening and treatment for hazardous and harmful alcohol and other substance use

Latest policy guidance

Consolidated guidelines on HIV, viral hepatitis and STI prevention, diagnosis, treatment and care for key populations
These guidelines outline a public health response for 5 key populations (men who have sex with men, trans and gender diverse people, sex workers, people...
Policy brief: Consolidated guidelines on HIV, viral hepatitis and STI prevention, diagnosis, treatment and care for key populations

The 2022 Consolidated guidelines on HIV, viral hepatitis and STI prevention, diagnosis, treatment and care for key populations outline a public health...

Recommended package of enabling and health interventions for HIV, viral hepatitis and STI prevention, diagnosis, treatment and care for trans and gender diverse people
This policy brief provides an update of the 2022 WHO Consolidated guidelines on HIV, viral hepatitis and STI prevention, diagnosis, treatment and care...

Publications

Recommended package of enabling and health interventions for HIV, viral hepatitis and STI prevention, diagnosis, treatment and care for trans and gender diverse people

In 2022, WHO published the Consolidated guidelines on HIV, viral hepatitis and STI prevention, diagnosis, treatment and care for key populations. These...

New good practice statement on counselling behavioural interventions for key populations to prevent HIV, viral hepatitis and STIs

Key populations (men who have sex with men, people who inject drugs, sex workers, trans and gender diverse people and people in prisons) are at increased...

Consolidated guidelines on HIV, viral hepatitis and STI prevention, diagnosis, treatment and care for key populations

The Consolidated guidelines on HIV, viral hepatitis and STI prevention, diagnosis, treatment and care for key populations outline a public health response...

WHO recommends social network-based HIV testing approaches for key populations as part of partner services package

Social network-based HIV testing is an approach for engaging sexual and drug injecting partners and social contacts of key population members with HIV...

Key considerations for differentiated antiretroviral therapy delivery for specific populations: children, adolescents, pregnant and breastfeeding women and key populations

In 2016, WHO published consolidated guidelines on the use of antiretroviral (ARV) drugs for treating and preventing HIV infection. As part of this revision,...

Consolidated guidelines on HIV prevention, diagnosis, treatment and care for key populations

In this consolidated guidelines document on HIV prevention, diagnosis, treatment and care for key populations, WHO brings together all existing guidance...

Tool to set and monitor targets for HIV prevention, diagnosis, treatment and care for key populations

This supplement provides technical guidance to assist countries in planning and monitoring efforts to address HIV among key populations: men who have sex...

Transgender people and HIV

This technical brief summarizes essential information and existing WHO recommendations for HIV prevention, diagnosis, treatment and care among transgender...

HIV AND YOUNG TRANSGENDER PEOPLE

Key populations at higher risk of HIV include people who sell sex, men who have sex with men, transgender people and people who inject drugs. Young people...

Consolidated guidelines on HIV prevention, diagnosis, treatment and care for key populations

In this new consolidated guidelines document on HIV prevention, diagnosis, treatment and care for key populations, the World Health Organization brings...

Values and preferences of key populations: consolidated report

Web annex to the WHO guideline: Consolidated guidelines on HIV prevention, diagnosis, treatment and care for key populations 

Guidance on oral pre-exposure prophylaxis (PrEP) for serodiscordant couples, men and transgender women who have sex with men at high risk of HIV

These recommendations have been developed specifically to address the daily use of antiretrovirals in HIV-uninfected people to block the acquisition of...

Prevention and treatment of HIV and other sexually transmitted infections among men who have sex with men and transgender people

The Guidelines focus on the prevention and treatment of HIV and other sexually transmitted infections (STIs) among men who have sex with men (MSM) and...

Article

Ensuring an inclusive global health agenda for transgender people, Bulletin of the World Health Organization,  March 2018, 95 (‎2)‎, 154 - 156, http://dx.doi.org/10.2471/BLT.16.183913

Regional publications