Treatment and care
Correct and effective treatment of sexually transmitted infections (STIs) – ideally given and taken on the same day, at the first contact between patients and health-care providers – is an important public health measure in the control of STIs, since it endeavours to break the chain of transmission of the infection without delay.
Countries should establish and use national standardized treatment protocols for STIs. Standardization ensures that all patients receive appropriate and adequate treatment at all levels of the health-care service. The protocols can also facilitate the training and supervision of health-care providers and help reduce the risk of development of resistance to antimicrobials. Finally, having a standardized list of antimicrobial agents can also facilitate procurement of the medicines.
STI case management
The purpose of comprehensive STI case management is to provide treatment, obtain cure, reduce the risk of developing complications from STIs, and reduce or prevent future infections. STI case management includes bio-behavioural interventions such as HIV pre-exposure prophylaxis (PrEP), voluntary medical male circumcision and ensuring that sex partners are appropriately treated. This requires that the patient receives the following services:
- medical and sexual history taken;
- correct diagnosis (whether syndromic or based on diagnostic tests);
- effective treatment;
- health education and counselling about the infection and risks;
- advice on compliance with treatment;
- promotion and/or provision of condoms (male or female);
- promotion and/or provision of HIV PrEP;
- promotion and/or provision of other preventive interventions, such as vaccines against hepatitis A and B and human papillomavirus, and voluntary medical male circumcision, where appropriate;
- partner services; and
- clinical follow-up, where appropriate.
Thus, effective case management consists not only of antimicrobial therapy to obtain cure and reduce infectiousness, but also the comprehensive assessment and care of a patient’s sexual and reproductive health and that of their sex partners.
Guidelines

Updated recommendations for the treatment of Neisseria gonorrhoeae, Chlamydia trachomatis, and Treponema...
The objectives of these present guidelines are: to provide updated evidence-informed guidance on treating infections caused by N. gonorrhoeae and C. trachomatis...

Recommendations for the treatment of Trichomonas vaginalis, Mycoplasma genitalium, Candida albicans,...
These guidelines focus on the treatment for infections caused by Trichomonas vaginalis, Mycoplasma genitalium and Candida albicans, and treatment for the...
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Consolidated guidelines on HIV, viral hepatitis and STI prevention, diagnosis, treatment and care for...
The Consolidated guidelines on HIV, viral hepatitis and STI prevention, diagnosis, treatment and care for key populations outline a public health response...

The WHO global health sector strategy on sexually transmitted infections (STIs), 2016–2021, endorsed by the World Health Assembly in 2016, aims to...

This guideline provides updated recommendations for syphilis screening for pregnant women based on the most recent evidence and available serologic tests...

Since the publication of the World Health Organization (WHO) Guidelines for the management of sexually transmitted infections in 2003, changes in the epidemiology...

WHO guidelines for the treatment of Chlamydia trachomatis
Since the publication of the WHO Guidelines for the management of sexually transmitted infections in 2003, changes in the epidemiology of STIs and advancements...

WHO guidelines for the treatment of Neisseria gonorrhoeae
Rationale for the guidelinesSince the publication of the WHO Guidelines for the management of sexually transmitted infections in 2003, changes in the epidemiology...

These guidelines provide updated recommendations for treatment of Treponema pallidum (syphilis) in adults and adolescents, including pregnant women, people...