e-Library of Evidence for Nutrition Actions (eLENA)


An online library of evidence-informed guidelines for nutrition interventions and single point of reference for the latest nutrition guidelines, recommendations and related information.

Alternate Text All interventions

Daily iron supplementation in adult women and adolescent girls

Intervention | Last updated: 20 June 2023


Globally, one in three non-pregnant women, corresponding to almost 500 million women, were anaemic in 2011. At least half of this anaemia burden is thought to be due to deficiency in iron, an essential nutrient for development and cell growth in the immune and neural systems, as well as in regulation of energy metabolism and exercise. Iron deficiency can result from inadequate intake or absorption of dietary iron, increased need during periods of growth, and blood loss from menstruation or helminth* infection. Because women of reproductive age lose iron through menstruation and their diets are often lacking in available iron, they are particularly vulnerable to iron deficiency.

Evidence has shown that daily iron supplementation is associated with reduced risk of anaemia and iron deficiency in menstruating women and adolescent girls, without any side effects.

* Helminths are a group of parasites commonly referred to as worms and include schistosomes and soil-transmitted helminths

WHO Recommendations


Daily iron supplementation is recommended as a public health intervention in menstruating adult women and adolescent girls living in settings where the prevalence of anaemia is 40% or higher in this age group, for the prevention of anaemia and iron deficiency.

Evidence


Systematic reviews used to develop the guidelines


Daily iron supplementation for improving iron status and health among menstruating women

Low MSY, Speedy J, Styles CE, De-Regil LM, Pasricha SR. Cochrane Database of Systematic Reviews. 2016; Issue 4. Art. No.: CD009747.

Summary of this review Alternate Text

Related systematic reviews


Iron Supplementation Benefits Physical Performance in Women of Reproductive Age: A Systematic Review and Meta-Analysis

Pasricha SR, Low M, Thompson J, Farrell A, De-Regil LM. J Nutr. 2014;144(6):906-14.


Cost-effectiveness Learn More Alternate Text


Relevant cost-effectiveness analyses have not yet been identified.