e-Library of Evidence for Nutrition Actions (eLENA)


An online library of evidence-informed guidelines for nutrition interventions and single point of reference for the latest nutrition guidelines, recommendations and related information.

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Iodine supplementation in pregnant and lactating women

Intervention | Last updated: 25 April 2023


Iodine is essential for healthy brain development in the fetus and young child. A woman’s iodine requirements increase substantially during pregnancy to ensure adequate supply to the fetus.

Most foods are relatively low in iodine content. To ensure that everyone has a sufficient intake of iodine, WHO and UNICEF recommend universal salt iodization as a global strategy. However, in certain countries salt iodization may not be feasible in all regions. Evidence suggests that in settings where universal salt iodization is not fully implemented, pregnant and lactating women and children under two years of age may not be receiving adequate amounts of iodized salt.

Depending on the percentage of households in a particular area with access to iodized salt, iodine supplementation may be necessary to ensure pregnant women are receiving adequate intake.

WHO Recommendations


WHO and UNICEF recommend iodine supplementation for pregnant and lactating women in countries where less than 20% of households have access to iodized salt, until the salt iodization programme is scaled up.

Countries with a household access to iodized salt between 20 and 90% should make efforts to accelerate salt iodization or assess the feasibility of increasing iodine intake in the form of a supplement or iodine fortified foods by the most susceptible groups.



Evidence


Related Cochrane reviews


Iodine supplementation for women during the preconception, pregnancy and postpartum period

Harding KB, Peña-Rosas JP, Webster AC, Yap CMY, Payne BA, Ota E, De-Regil LM.Cochrane Database of Systematic Reviews 2017, Issue 3. Art. No.: CD011761.

Summary of this review Alternate Text

Related systematic reviews


The Effects of Iodine Deficiency in Pregnancy and Infancy

Zimmermann MB. Paediatric and Perinatal Epidemiology. 2012; 26: 108–117.


Iodine and mental development of children 5 years old and under: a systematic review and meta-analysis

Bougma K, Aboud FE, Harding KB, Marquis GS. Nutrients. 2013;5:1384-416.


Effect of iodine supplementation in pregnancy on child development and other clinical outcomes: a systematic review of randomized controlled trials

Zhou SJ, Anderson AJ, Gibson RA, Makrides M. American Journal of Clinical Nutrition. 2013; 98(5):1241-54.