e-Library of Evidence for Nutrition Actions (eLENA)


An online library of evidence-informed guidelines for nutrition interventions and single point of reference for the latest nutrition guidelines, recommendations and related information.

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Daily iron supplementation in children 24–59 months of age

Intervention | Last updated: 20 June 2023


Approximately 300 million children globally had anaemia in 2011. The most common cause of anaemia is thought to be deficiency in iron, an essential nutrient for development and cell growth in the immune and neural systems, as well as in regulation of energy metabolism and exercise. Iron deficiency can result from inadequate intake or absorption of dietary iron, increased need during periods of growth, and blood loss from helminth* infection.

Children are particularly vulnerable to iron deficiency anaemia because of their increased iron requirements in the periods of rapid growth, especially in the first five years of life. Iron deficiency anaemia in children has been linked to increased childhood morbidity and impaired cognitive development and school performance.

Evidence has shown that daily iron supplementation in children 24-59 months of age is associated with increased ferritin (an indicator of iron stores and a biomarker for iron deficiency) and haemoglobin** levels.

* Helminths are a group of parasites commonly referred to as worms and include schistosomes and soil-transmitted helminths
** Haemoglobin is a molecule that allows red blood cells to transport oxygen throughout the body

WHO Recommendations


Daily iron supplementation is recommended as a public health intervention in preschool-age children aged 24–59 months, living in settings where the prevalence of anaemia in infants and young children is 40% or higher, for increasing haemoglobin concentrations and improving iron status.

Cost-effectiveness Learn More Alternate Text


Relevant cost-effectiveness analyses have not yet been identified.