Health products policy and standards
Our team provides authoritative guidance and standards on quality, safety and efficacy of health products and supports countries to formulate evidence-based policies and ensure good practice throughout the value chain.

International Nonproprietary Names Programme and Classification of Medical Products

International Nonproprietary Names (INN)

International Nonproprietary Names (INN) facilitate the identification of pharmaceutical substances or active pharmaceutical ingredients. Each INN is a unique name that is globally recognized and is public property. A nonproprietary name is also known as a generic name.

Mandate

WHO has a constitutional mandate to "develop, establish and promote international standards with respect to biological, pharmaceutical and similar products".

The World Health Organization collaborates closely with INN experts and national nomenclature committees to select a single name of worldwide acceptability for each active substance that is to be marketed as a pharmaceutical. To avoid confusion, which could jeopardize the safety of patients, trade-marks should neither be derived from INNs nor contain common stems used in INNs. The selection and publication of INNs falls under the responsibility of the EMP/RHT/TSN team of the INN Programme. 

Guidance on INN

Nonproprietary names are intended for use in pharmacopoeias, labelling, product information, advertising and other promotional material, drug regulation and scientific literature, and as a basis for product names, e.g. for generics. Their use is normally required by national or, as in the case of the European Community, by international legislation. As a result of ongoing collaboration, national names such as British Approved Names (BAN), Dénominations Communes Françaises (DCF), Japanese Adopted Names (JAN) and United States Adopted Names (USAN) are nowadays, with rare exceptions, identical to the INN.

Dr R. Balocco Mattavelli

World Health Organization
International Nonproprietary Names
(MHP/HPS/INN)
20 Avenue Appia
1211, Geneva 27
Switzerland
Tel: +41 22 791 1249
Fax: +41 22 791 4730


Publications

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INN Pre-Stem Icon

The step before the adoption of an INN stem by the INN Expert Group is to publish them as a pre-stem in order to collect possible issues.

INN Stem Book Addendum Icon

The document "Use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances" is intended primarily for persons...

INN Nomenclature Schema Icon

-tug for “unmodified immunoglobulins”The suffix -tug is used for monospecific full-length immunoglobulins with unmodified constant...

Last INN Consultation Executive Summary

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Icons INN Executive Summary

During the 79th INN Consultation, 281 INN requests were discussed, including:• 249 new INN requests, of which 155 were for biological substances•...

Icons INN Executive Summary

During the 78th INN Consultation, 288 INN requests were discussed, including:• 261 new INN requests, comprising:   o 129 chemical substances ...

Icons INN Executive Summary

During the 77th INN Consultation, 252 INN requests were discussed, including:• 217 new INN requests, of which 146 were for biological substances•...

Last INN Recommended Lists

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INN Recommended List  Icon

Notice is hereby given that, in accordance with article 3 of the Procedure for the Selection ofRecommended International Nonproprietary Names for Pharmaceutical...

INN Recommended List  Icon
17 November 2024

INN Recommended List 92

Notice is hereby given that, in accordance with article 3 of the Procedure for the Selection ofRecommended International Nonproprietary Names for Pharmaceutical...

INN Recommended List  Icon

Notice is hereby given that, in accordance with article 3 of the Procedure for the Selection ofRecommended International Nonproprietary Names for Pharmaceutical...

Last INN Proposed Lists

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INN Proposed List Icon
13 February 2025

INN Proposed List 132

Notice is hereby given that, in accordance with article 3 of the Procedure for the Selection of Recommended International Nonproprietary Names for Pharmaceutical...

INN Proposed List Icon

Notice is hereby given that, in accordance with article 3 of the Procedure for the Selection of Recommended International Nonproprietary Names for Pharmaceutical...

INN Proposed List Icon
29 February 2024

INN Proposed List 130

Notice is hereby given that, in accordance with article 3 of the Procedure for the Selection of Recommended International Nonproprietary Names for Pharmaceutical...