
REPLACE
Trans Fat-Free

An action package to eliminate industrially-produced trans fat from the global food supply
Since WHO first called for the global elimination of industrially produced trans fat in 2018, remarkable progress has been achieved with population coverage of best-practice trans fat elimination policies increasing more than six-fold globally.
High intake of trans fat (>1% of total energy intake) is associated with increased risk of coronary heart disease and mortality. Eliminating trans fat is a powerful way to prevent heart disease and the high costs it incurs for individuals and economies in medical treatment and lost productivity. WHO remains committed in supporting countries in their efforts to eliminate industrial trans fats for good and in celebrating their achievements to this end.
WHO calls for accelerated action till 2025 to complete this effort and remains committed to supporting countries in their efforts and celebrating their achievements.
The REPLACE action package provides a strategic approach to eliminating industrially-produced trans fat from national food supplies.
The package comprises an overarching technical document that provides a rationale and framework for this integrated approach to trans fat elimination, along with six modules and additional web resources to facilitate implementation.
The six areas of action include:
REview dietary sources of industrially-produced trans fat and the landscape for required policy change.
Promote the replacement of industrially-produced trans fat with healthier fats and oils.
Legislate or enact regulatory actions to eliminate industrially-produced trans fat.
Assess and monitor trans fat content in the food supply and changes in trans fat consumption in the population.
Create awareness of the negative health impact of trans fat among policy-makers, producers, suppliers, and the public.
Enforce compliance with policies and regulations.
News
Modules

Publications

This fifth milestone report summarizes the progress from 2018-2023 towards the global elimination of industrially produced trans-fatty acids (TFA), highlighting...

Countdown to 2023: progress of selected international food and beverage companies towards eliminating...
In support of the WHO’s goal of eliminating industrially produced trans-fatty acids (iTFA) from the global food supply by 2023, 11 members...

Simplified protocol for measuring trans-fatty acids content as a percentage of total fatty acids in food...
Assessing and monitoring TFA content in the food supply and changes in trans-fatty acids (TFA) consumption in the population is one of the key...

Saturated fat and trans-fat intakes and their replacement with other macronutrients: a systematic review...
Together with other modifiable risk factors such as physical inactivity, tobacco use and harmful use of alcohol, unhealthy diets – including high...

REPLACE trans fat: an action package to eliminate industrially produced trans-fatty acids
Elimination of industrially produced trans-fatty acids (TFA) from the food supply is one of the priority targets identified in the draft 13th General Programme...

Global protocol for measuring fatty acid profiles of foods, with emphasis on monitoring trans-fatty acids...
Provides a globally harmonized method to measure trans fats in foods. It will enable countries to assess the levels of trans-fatty acids (TFA) in...

REPLACE, the WHO Action Package and guide to global elimination of trans fat, provides a six step action package including enacting regulations to strictly...

Eliminating industrially-produced trans fat from the world food supply and replacing them with healthier oils could save more than 500,000 lives per year. The...
Toolkit

Nutrition and Food Safety News - April 2025

Nutrition and Food Safety News - March 2025
This edition of the NFS Newsletter features key activities we undertook in February and early March 2025.

Nutrition and Food Safety News - February 2025
The latest edition of our NFS Newsletter features key activities we undertook in December 2024-January 2025.
Annual reports

This fourth annual report monitors global progress towards the 2023 target for global elimination of industrially produced trans-fatty acids (TFA), highlighting...

This third annual report monitors global progress towards the 2023 target for global elimination of industrially produced trans-fatty acids (TFA), highlighting...

Countdown to 2023: WHO report on global trans-fat elimination 2020
In 2018, TFA elimination was identified as one of the priority targets in the World Health Organization (WHO) 13th General Programme of Work, which guides...

Countdown to 2023: WHO report on global trans-fat elimination 2019
In May 2018, the World Health Organization (WHO) launched the REPLACE action package to support governments to eliminate industrially produced TFA from...
Events
Fact sheets
Podcast
More information
Support
The following organizations support the REPLACE modules:
- American Heart Association
- Centre for Chronic Disease Control (CCDC)
- NCD Alliance
- Resolve to Save Lives
- World Heart Federation