Product & Delivery Research
IVB’s Product and Delivery Research (PDR) unit aims to accelerate development and evidence-based use of vaccines against pathogens with significant disease and economic burden in low- and middle-income countries (LMICs).

Roadmaps

Roadmaps

Vaccine development technology or R&D roadmaps are pathogen-specific, developed in collaboration with global stakeholders and aim to highlight priority activities to accelerate the pathway to licensure, availability and access in low- and middle-income countries (LMICs).  The target audience is vaccine researchers, funders and product developers. Roadmaps have been developed for several pathogens and can be accessed under ‘Research by disease’.

Pathogen-specific Roadmaps

Sexually-Transmitted Infections

  • Gottlieb SL, Deal CD, Giersing B, Rees H, Bolan G, Johnston C, Timms P, Gray-Owen SD, Jerse AE, Cameron CE, Moorthy VS, Kiarie J, Broutet N. The global roadmap for advancing development of vaccines against sexually transmitted infections: Update and next steps. Vaccine. 2016 Jun 3;34(26):2939-2947. doi: 10.1016/j.vaccine.2016.03.111. Epub 2016 Apr 19. PMID: 27105564; PMCID: PMC6759054. 
  • Gottlieb SL, Jerse A, Delany-Moretlwe S, Deal C, Giersing  B. Advancing vaccine development for gonorrhoea and the Global STI Vaccine Roadmap. Sex Health. 2019 Sep;16(5):426-432. doi: 10.1071/SH19060. Available at: https://pubmed.ncbi.nlm.nih.gov/31476278/ 

Tuberculosis

Respiratory syncytial virus (RSV)


Group B Streptococcus

  • Vekemans J, Moorthy V, Friede M, Alderson MR, Sobanjo-Ter Meulen A, Baker CJ, Heath PT, Madhi SA, Mehring-Le Doare K, Saha SK, Schrag S. Maternal immunization against Group B streptococcus: World Health Organization research and development technological roadmap and preferred product characteristics. Vaccine. 2019 Nov 28;37(50):7391-3. Available at: https://www.sciencedirect.com/science/article/pii/S0264410X17313592

Antimicrobial Resistance

An Action Framework and annexe to Immunization Agenda 2030

Invasive non-typhoidal Salmonella (iNTS)

Research and development technology roadmap for invasive non-typhoidal Salmonella vaccines against invasive disease
Invasive non-typhoidal serovars of Salmonella enterica, S. Typhimurium and S. Enteritidis, (iNTS) were estimated to cause over 500 000 invasive disease...